https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Inhibition of γ-glutamyl transferase suppresses airway hyperresponsiveness and airway inflammation in a mouse model of steroid resistant asthma exacerbation https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52589 Wed 28 Feb 2024 15:29:42 AEDT ]]> Understanding the mechanisms of bacterial-induced exacerbation of allergic airways disease in a mouse model https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30418 Wed 11 Apr 2018 18:44:50 AEST ]]> Modeling of respiratory syncytial virus-induced exacerbation of allergic airways disease https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27889 Wed 11 Apr 2018 14:53:06 AEST ]]> Airway IL-1β and systemic inflammation as predictors of future exacerbation risk in asthma and COPD https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25075 Wed 11 Apr 2018 12:27:25 AEST ]]> Proteomic Analysis Reveals a Novel Therapeutic Strategy Using Fludarabine for Steroid-Resistant Asthma Exacerbation https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45231 Thu 27 Oct 2022 12:56:33 AEDT ]]> Single-cell transcriptomic analysis reveals the immune landscape of lung in steroid-resistant asthma exacerbation https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48011 + memory T cells were the predominant sources of interleukin (IL)-4 and IL-13 transcripts whose expressions were dexamethasone resistant. Production of IL-13 by these cells was validated by IL-13-reporter mice. Neutralization of IL-13 abolished HDM/LPS-induced airway hyperresponsiveness, airway inflammation, and decreased mucus hypersecretion. Furthermore, using Ingenuity Pathway Analysis systems, we identified canonical pathways and upstream regulators that regulate the activation of basophils, ILC2, and CD8⁺ memory T cells. Our study provides mechanistic insights and an important reference resource for further understanding of the immune landscape during asthma exacerbation.]]> Thu 23 Mar 2023 10:07:13 AEDT ]]> Validity of the common cold questionnaire (CCQ) in asthma exacerbations https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:4455 Sat 24 Mar 2018 10:12:16 AEDT ]]> An umbrella review: corticosteroid therapy for adults with acute asthma https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7009 Sat 24 Mar 2018 08:38:05 AEDT ]]> Characterization of innate immune signalling receptors in virus-induced acute asthma https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:12549 Sat 24 Mar 2018 08:16:34 AEDT ]]> Current asthma control predicts future risk of asthma exacerbation: a 12-month prospective cohort study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:23529 Sat 24 Mar 2018 07:13:47 AEDT ]]> Enhanced Pro-Inflammatory Response of Macrophages to Interleukin-33 in an Allergic Environment https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48817 Mon 20 Nov 2023 09:47:33 AEDT ]]> In vivo experimental models of infection and disease https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:40023 Mon 04 Jul 2022 09:22:32 AEST ]]> Development of airway epithelial targeted nanoparticles loaded with TLR7 agonist for asthma therapy https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:37876 Fri 28 May 2021 12:47:02 AEST ]]>